Just double-click on the !BootSparQ application. This may be run from floppy disc or you can copy it to a suitable location on your hard disc.
The software supplied by Syquest is suitable only for use with DOS, Windows 3.1, Windows 95 and NT. If you are using Windows XP then this software won't work. However APDL do have a later driver which works with XP and this can be downloaded from the APDL web site.
Note that I'm not sure if either driver works on Windows 98 or 2000 and although I've been told that the later software works with Vista I haven't actually tried it.